One of the more common requests that Exchange adminsitrators get it to allow an assistant to be able to send email as another person.
Source: http://support.microsoft.com/?kbid=327000
If you grant a user "Send on behalf" permissions for another user's mailbox, that user can send mail on behalf of the mailbox owner. The name in the From box of these messages appears as
where DelegateUser is the name of the user to whom you granted "Send on behalf" permissions and where MailboxOwner is the name of the user who owns the mailbox. To grant a user "Send on behalf" permissions for another user's mailbox:
If you grant a user "Send as" permissions for another user's mailbox, the DelegateUser can send mail as the MailboxOwner. The From box in these messages appears as follows:
To grant a user "Send as" permissions for another user's mailbox:
- Joel